Klippel-Trenaunay Syndrome

BMJ Case Report 2012 Jun 14;2012. pii: bcr2012006226. doi: 10.1136/bcr-2012-006226.

Closure of non-healing chronic ulcer in Klippel-Trenaunay syndrome using low-level laser therapy.

Dixit S, Maiya AG, Umakanth S, Shastry BA.


Department of Physiotherapy, MCOAHS, Manipal University, Karnataka, India.


A 69-year-old man diagnosed with Klippel-Trenaunay syndrome (KTS) reported to the physiotherapy outpatient clinic with the complaint of a non-healing ulcer over the right medial malleolus, for a 6-month duration, that was non-granulating and had moderate pus discharge with foul odour at initial assessment. There was a decrease in scores of the Pressure Ulcer Scale of Healing, a significant increase in granulation tissue, a decrease in the amount of discharge and foul odour along with complete closure of the chronic wound after irradiation with a light-emitting diode (LED). This is a novel case study analysing the possible effect of a helium-neon laser  and LEDs on non-healing chronic ulcers associated with KTS, where the complete closure of the chronic ulcer that was initially not responsive to standard medical care was observed.