Acta Cir Bras. 2009 Jan-Feb;24(1):7-12.
Evaluation of low intensity laser's action on silicone mammary implant pseudocapsules in rats.
Palhares A, Schellini SA, Pellizzon CH, Padovani CR, Dorsa P.
Department of Surgery and Orthopedic, Botucatu Faculty of Medicine, State University of Sao Paulo, Brazil. firstname.lastname@example.org
PURPOSE: To evaluate the effect of low intensity laser on the pseudocapsule contraction that occurs around silicone implants.
METHODS: 60 male rats divided in two experimental groups received a silicone implant in the subcutaneous of the dorsal region. Group I: animals received implants in the subcutaneous dorsal region and did not receive any treatment; Group II: animals received seven irradiation sessions with low intensity laser after they had received subcutaneous implants. Thirty, 60 and 180 days after the surgery, tonometric evaluation of the implants was conducted. After that, the animals were sacrificed, study material was removed and prepared for histological examination. The thickness of the pseudocapsule and the inflammatory reaction were morphometrically quantified. Data obtained were statistically analyzed using the Variance method, and Tukey's Test(P<0.0 5).
RESULTS: Group II animals had significant lower pressure. The histological study did not show a significant difference between the groups, but only a higher number of swollen vessels in Group II. The thickness of pseudocapsule around Group II's implants lower than in Group I.
CONCLUSION: The low intensity laser modify tissue's reparation process around the implants suggesting it may be useful to model contractures that are formed around silicone implants.